Common side effects of Anadrol include depression, drowsiness, headache, swelling, rapid weight gain, abnormal erections, skin color changes, nausea, loss of appetite, insomnia, and more. However, the main side effects of Anadrol are hepatotoxicity and hypertension.
Anadrol is a C17-alpha-alkylated compound that protects it from inactivation through the liver. This gives Anadrol good oral activity, remaining active in the blood when taken orally.
At the same time, as with all C17-alpha-alkylated AAS, they cause stress to the user's liver.
Because Anadrol has A saturated A ring, this reduces its hepatotoxicity to some extent; However, studies have shown that it can affect liver health if taken in high doses.
In a 2003 study of 89 subjects taking 100-150mg of Anadrol daily for 16 weeks, ALT/AST liver enzymes increased more than five-fold in 25% of the 100mg group and more than five-fold in 43% of the 150mg group.
Therefore, the risk of liver damage significantly increase when use Anadrol at high doses and over a long period of time.
As a result, the bodybuilder's Anadrol dosage keep below 100mg per day.
In another study of 31 subjects taking 50 to 100mg of Anadrol daily, the 50mg group did not show any increase in liver enzymes, but the 100mg group showed moderate ALT/AST increase.
When bodybuilder uses Anadrol to assist bodybuilding, precautions should be taken by using low to moderate doses of Anadrol over a relatively short period (4-6 weeks) and, if necessary, some liver-protecting medication.
High blood pressure is another problem. Basically all AAS affect bodybuilder blood pressure because exogenous testosterone causes negative changes in cholesterol levels. This leads to a sharp rise in LDL cholesterol levels and a drop in HDL levels.
Anadrol's study showed it had a negligible effect on LDL levels, but led to a rapid drop in HDL levels.
In an experiment of 31 subjects, taking 50-100mg of Anadrol daily reduced their HDL by 19 and 23 points, respectively.
Since Anadrol significantly increases red blood cell count, it also increases blood pressure. Anadrol users have five times the number of red blood cells. As a result, the user's blood becomes more viscous and blood flow to the heart may be impaired. Water retention further reduces circulation.
Anadrol is an AAS that has negative effects on the heart due to its effects on HDL cholesterol levels, red blood cell count, and water retention. Bodybuilders with high blood pressure or a family history of heart disease should avoid Anadrol.
Nosebleeds and headaches may occur when taking Anadrol's bodybuilder, which may be a sign of elevated blood pressure.