Common side effects of Anadrol include depression, drowsiness, headache, swelling, rapid weight gain, abnormal erections, skin color changes, nausea, loss of appetite, insomnia, and more. However, the main side effects of Anadrol are hepatotoxicity and hypertension. Anadrol side effects Hepatotoxicity Anadrol is a C17-alpha-alkylated compound that protects it from inactivation through the liver. This …