SERM clomid and Tamoxifen, both of which are used in PCTS. So, clomid vs tamoxifen, which should I choose?
Clomid is a non-steroidal SERM that promotes the release of GnRH with more FSH(follicle-stimulating hormone) and LH(luteinizing hormone). FSH and LH help increase the body's testosterone levels and are important when the bodybuilder is affected by exogenous AAS causing testosterone suppression.
In addition to increasing the gonadotropin, Clomid also binds to estrogen receptors, making it an important aid in treating pregnant women and men, since excess estrogen can affect our reproductive system.
Clomid prevents this from happening by preventing estrogen from reaching the pituitary gland, where it has an antagonistic effect.
Tamoxifen is also a selective estrogen receptor modulator (SERM), which has certain estrogen effects, and is also used as an estrogen antagonist, whose main effect is to eliminate the adverse effects of estrogen.
It works by binding to estrogen receptors in specific parts of the body. Tamoxifen works mainly by blocking estrogen in breast tissue so that estrogen cannot attach to breast cells, thus avoiding gynecomastia.
It bind to the appropriate estrogen receptor, and the estrogen already present in the body can no longer bind to the estrogen receptor, thus reducing the effect of estrogen on breast tissue.
Clomid is commonly used with tamoxifen by bodybuilder at pct cycle. When used together, these two SERMs can be safely administered at lower doses and provide significant results.
Gynecomastia is a common side effect of AAS. Although it is not a dangerous disease, it can have serious consequences for one's self-esteem. Gyno is caused by the production of estrogen from exogenous AAS after they are aromatized in the body by aromatase. Excess estrogen levels in men promote feminine characteristics such as breast tissue development. In many cases, gynecomastia only results in the storage of tiny fat clumps above or around the male nipple, or sometimes puffiness of the nipple.
Tamoxifen treats breast cancer by targeting breast tissue. Tamoxifen binds to estrogen receptors in the breast region, effectively preventing estrogen from acting there and thereby preventing breast development in men.
From the above we can know that Clomid vs tamoxifen both block the effect of estrogen. Clomid focuses on blocking the effects of estrogen gonadotropin. Tamoxifen focuses on blocking the effect of estrogen on breast development in men. When pct cycle is mainly for solving the Gyno problem, tamoxifen can be used only. Clomid is required if there is a problem with reduced testosterone levels in addition to male breast development after an AAS cycle. Of course, Clomid also helps with gynecomastia. In fact, most people use Clomid and Tamoxifen together.