Sarm is used for bodybuilding, then, can sarm mk677 benefits for height increase?
When taken orally, the growth hormone secretagotin MK677 stimulates the production of growth hormone (GH). Therefore, MK677 can definitely help increase height.
Under normal circumstances, human GH is secreted by the pituitary gland. Then, for people with insufficient pituitary function. Can mk677 promote the secretion of GH by the pituitary gland and help them grow taller?
Several human trials have explored this question. One trial studied nine men aged 17-34 who had idiopathic GH deficiency in childhood and had not been treated with GH or GH secretagine for at least six months prior to the study.
The study was divided into two groups. The first group of four people received placebo and 10mg mk677 in a cross-over manner. And the second group of five people received 10mg mk677 during the first study and 50mg mk677 during the second study.
The results showed that there was a significant increase in GH,IGF-1, and IGFBP-3 circulating concentrations in patients treated with 10mg and 50mg mk677 orally per day, while there was no change in parameters in patients treated with placebo.
Before taking mk677, all subjects had GH levels below the normal range for the current age group. And after treatment with two doses of mk677, all subjects had GH levels above baseline concentration. And mk677 had similar stimulative effects in doses of 10 and 50mg.
This experiment showed that mk677 can help men with GH deficiency increase GH level and help to grow taller.
The increased IGF-1 and GH concentrations induced by mk677 as a GH secretagogue are most likely due to the effects on the pituitary and hypothalamus. All subjects had measurable, albeit reduced, serum GH levels, indicating idiopathic GH deficiency. This is caused by insufficient stimulation of the pituitary gland by GHRH in the hypothalamus, rather than a primary lesion of the pituitary gland. Therefore, it is possible to treat this symptom with not only HGH but also GH secretagotin mk677. The GH secretagogue mk677 has no effect on primary pituitary lesions where the concentration of GH in vivo is almost undetectable. In fact, the proportion of people with such severe deficiency is less than 25% of the GH deficiency.
Therefore, MK677 treatment can increase the level of GH in the body for common GH deficiency.
Mk677 helps to increase the level of GH in the body. But it does not mean that mk677 can help to grow taller, which depends on whether the user's bones have been closed. For people who have been closed, using mk677 will not grow taller. Again, using HGH in this case will not increase the height.