Growth Hormone:MK677 VS HGH which is better for you

MK677 SARM is a selective androgen receptor agonist (SARM), MK677 also known as Ibutamoren, which is a ghrelin receptor and growth hormone secretion agent that increases the secretion of growth hormone (GH) and insulin-like growth factor 1 (IGF-1) by mimicking the endogenous hormone ghrelin on growth hormone (GH), increasing plasma levels of these two hormones but not affecting cortisol levels. It is well known that recombinant human growth hormone (HGH) is a synthetic form of growth hormone that can promote elevation of human growth hormone. Let's learn more about MK677 VS HGH

MK 677 vs HGH, what comes to mind when you see this keyword? Why is one Sarms and the other a peptide, but will the two be compared? To figure this out, let's first get to know about the MK677

MK677 SARM Basic Information

Product name: MK677
Other names: Ibutamoren; MK-677
CAS:159752-10-0
Molecular Formula: C28H40N4O8S2
MW: 624.776
Zip code: 1308068-626-2
Appearance: White powder
Min. Order: 10g
Test method: High performance liquid chromatography
Packing: 10g, 100g, 500g and 1kg

MK677 Sam History

MK677, a growth hormone secretion enhancer (GHS) originally developed to combat symptoms such as muscle atrophy, obesity and osteoporosis, is also targeted at elderly patients with hip fractures. Therefore, medical institutions have conducted more research on MK677.

The institute found in its research related to fitness activities that:

In one catabolic study, healthy young men who took 25 mg of MK677 per day showed a sustained increase in serum IGF-1 and growth hormone (GH) concentrations after 7 days.

A study conducted in the treatment of osteoporosis and bone mineral density showed that bone density increased after the use of MK677, so MK677 had a positive effect on bone mineral density.

As researchers continue to study MK677, MK677 has shown positive effects in the field of bodybuilding. In recent years, MK677 has gained more and more applications in the field of bodybuilding.

MK677 SARM mechanism of action

MK677 SARM is a growth hormone receptor agonist and growth hormone secretion agent that mimics the secretory effect of the endogenous hormone ghrelin on growth hormone (GH). It does not act directly on androgen receptors, so Mk677 is not a strict SARM. But many supplement manufacturers classify it as SARM.

MK677 increases the secretion of growth hormone (GH) and islet-like growth factor 1 (IGF-1) but does not affect plasma cortisol levels.

1. Growth hormone (GH) is used in bodybuilding

Human Growth hormone (GH) is a potent anabolic hormone that promotes linear growth, weight gain, and systemic nitrogen retention. Growth hormone (GH) therapy has been shown to increase muscle mass in older men and promote protein accumulation in subpituitary subjects. These anabolic features suggest that it may be helpful in the treatment of catabolic patients, especially those caused or worsened by inadequate caloric intake. The anabolic effects of growth hormone (GH) have been used to partially reverse dietary energy restriction, exercise, surgical over-energy utilization, glucocorticoid excess catabolic effects and aging. Unfortunately, while recombinant human growth hormone (HGH) is available, treatment with growth hormone is expensive and requires parenteral administration. Therefore, growth hormone secretion agents such as MK677, which stimulate endogenous growth hormone (GH) secretion, are reasonable alternatives. It can help improve the body's anabolic metabolism and increase protein synthesis, thereby promoting muscle gain in bodybuilders. This is good for bodybuilders.

2. Islet-like growth factor 1 (IGF-1) is used in bodybuilding

IGF-1 is released in the liver and binds to intracellular IGF receptors, eventually leading to stimulation of cell growth (both lead to the formation of new tissues and the growth of existing tissues) and inhibition of cell death. It is a highly anabolic and anti-catabolic compound. For bodybuilders, this has many positive effects: increased nitrogen retention and protein synthesis because it is highly anabolic. IGF-1 (in the presence of sufficient protein) promotes the growth of new muscle cells, which increases the total number of cells in the muscle. IGF can also protect brain neurons, promoting the growth of new motor neurons, allowing them to learn new skills faster during use. IGF-1 is also responsible for connective tissue production, improving collagen formation, and aiding in cartilage repair. Similarly, it affects bones by aiding in bone building and repair.

Through the above introduction, it can be understood that the mechanism of action of MK677 is to promote the secretion of growth hormone (GH) and islet-like growth factor 1 (IGF-1). MK677 can increase growth hormone (GH) and islet-like growth factor-1 (IGF-1) in the body to improve the body's anabolism, increase the body's protein synthesis, improve muscle mass, and improve the body's bone quality.

MK677 and growth hormone secretagogue (GHS) receptor agonists

Growth hormone secretagogue (GHS) receptor agonists are divided into peptides and non-peptides, and peptides include GHRP-2 and GHRP-6. And MK677 belongs to the oral non-peptide class.

Ghrp-6 and GHRP-2 are the best-known growth hormone releasing peptides (GHRP). They also stimulate growth hormone production by activating ghrelin receptors, but GHRP-6 and GHRP-2 have shorter half-lives and require multiple daily dosing. Furthermore, the peptide structures of GHRP-6 and GHRP-2 make them injectable only. Multiple daily injections can leave visible marks on the skin.

Ghrp-6 was the first ghrelin to be developed, and MK-677 was derived from its molecule. Therefore, MK677 naturally has a growth hormone peptide-like effect.

SARM MK677 is a non-peptide ghrelin (GHS) receptor agonist and a growth hormone secretagogue that is orally available, making it easier to use when switching from injection to oral administration. MK677 also has a longer half-life and can be used once a day, which further improves the user's experience.

 MK677 VS HGH

It is well known that growth hormone (GH) plays an important role in the human body, and an increase in growth hormone (GH) has many benefits for the body. With the development of science and technology, the recombinant human growth hormone (HGH) synthesized in vitro came into being. Recombinant human growth hormone (HGH) is produced by secretory expression technology in recombinant E. coli. It consists of 191 amino acids. Its amino acid content, spatial conformation and sequence are exactly the same as the growth hormone secreted by the human body. Its role is the same as the growth hormone secreted by the body itself.

So why not just use recombinant human growth hormone?

Recombinant human growth hormone (HGH) can only be administered by injection, which is expensive and requires daily injections. MK677 is an oral growth hormone secretagogue (GHS) receptor agonist for MK677 VS HGH. After oral administration, it promotes the secretion of growth hormone (GH) and islet-like growth factor 1 (IGF-1). By using ibutamoren/MK-677 powder, you can easily get an amazing boost to your own natural growth hormone pulse without having to deal with the annoying and painful daily HGH injections. Meanwhile, ibutamoren/MK-677 powder can be used for a variety of reasons, from increasing muscle mass to shredding. It does not compete with the levels of growth hormone available from exogenous HGH, so you can use it with your hgh cycle.

In conclusion, MK677 combines the functions of SARMs and growth hormone peptides, and has its own advantages, such as: no treatment cycle; oral administration, no need for multiple injections a day; increase muscle and reduce fat at the same time; accelerate wound healing and repair damage, etc.

The above makes the MK677 quickly become the consensus choice of bodybuilding enthusiasts.

So for MK677 VS HGH, MK677 can also be used with many bodybuilding SARMs and can be used in exactly the same way as SARMs.

MK 677 Benefits

The benefits of MK-677 include muscle building, reduction in muscle wasting, improved bone density, improved sleep and anti-aging properties. It may also have nootropic properties and help treat growth hormone deficiency.

1.Helps build muscle 

MK677 powder for bodybuilding stimulates the production of growth hormone and IGF-1, thereby improving the body's anabolic capacity, and studies have shown that it increases muscle mass and promotes the accumulation of protein, an important component of muscle. While MK-677 is able to increase growth hormone production, users can experience a significant increase in muscle growth recovery. Therefore MK-677's ability to increase growth hormone production makes it a popular choice.

2.Reduce muscle wasting 

Muscle atrophy is a frequent problem with bodybuilders, although bodybuilders are doing proper training. Experts believe there is a link between muscle wasting and a lack of protein in the diet. Several studies suggest that Mk-677 prevents this unwanted muscle wasting and eliminates protein catabolism.

3.Increase bone density 

MK677 promotes the secretion of islet-like growth factor 1 (IGF-1), which is responsible for connective tissue production, improves collagen formation and aids in cartilage repair. Likewise, it affects bones by helping with bone generation and repair. Therefore, MK677 can help bodybuilders increase bone density for better training, and also help the elderly to solve the problem of osteoporosis.

4.Improve sleep 

Since growth hormone improves sleep quality, and MK677 increases growth hormone production, it may help improve sleep quality.

5.Anti-aging and longevity 

With the increase of age, the secretion of various hormones in the human body will gradually decrease, and MK677 can increase the production of hormones and the production of IGH-1, so the elderly taking MK677 can improve the overall hormone status in the body.

6.May have nootropic effects

Because MK677 improves sleep quality, getting the right amount of sleep each night is important as we strive to achieve adequate cognitive function. MK-677 may improve cognitive function by helping individuals get a good night's rest. Based on the role of IGF-1 in cognitive function, the ability of MK-677 to stimulate IGF-1 production may also indirectly improve cognitive function.

7.Beneficial in the treatment of growth hormone deficiency 

MK677 increases growth hormone IGF-1 levels in children with growth hormone deficiency, while MK677 does not increase concentrations of any undesirable hormones such as cortisol. So beneficial for growth hormone deficiency.

MK677 for Women 

Bodybuilders usually use MK677 as a selective androgen receptor (SARM), but MK677 is not actually a SARM, it does not directly interact with the androgen receptor (AR), it belongs to a growth hormone secretagogue (GHS) receptor Agonists promote the secretion of human growth hormone (GH) and islet-like growth factor 1 (IGF-1). MK677 does not have the same virilizing effect on women as anabolic steroids. So MK677 is suitable for female bodybuilders.

MK677 side effects

Numerous studies have shown that even long-term use of MK677 is well tolerated. There are not many side effects that need to be noticed during the use of bodybuilders, but due to the difference in human body, Bodybuilders still needs to understand it in detail before using it, including dosage and cycle.

Improper dosage and irregular long-term use may have side effects, here are some potential MK677 side effects:

increased appetite

fatigue and lethargy

decreased insulin sensitivity

Elevated blood sugar levels

One of the most obvious side effects of MK677 is increased water retention, which is a clear effect of increased growth hormone (GH) levels. So it's more suitable for puffing than cutting.

For bodybuilders, proper dosage and regular use generally do not cause side effects.

MK677 Dosage and cycle 

When bodybuilders are using MK677, the dosage and cycle used need to be considered. For starters, they often need to start with low doses, and even small doses of MK 677 can have a very positive effect on growth hormone levels, overall muscle growth, REM sleep quality, and more. For advanced bodybuilders, start with the maximum dose for better results.

Dosage and Cycles for Men

Dosage:

Beginner: 10 mg per day

Intermediate: 25 mg per day

Advanced: 50 mg per day

MK677 powder for bodybuilding has a half-life of 6 hours, so it is best to use it in different doses. However, if side effects such as increased hunger and drowsiness become excessive, the total daily dose should be reduced each day around 6pm.

Because of the compound's sleep-enhancing properties, the adaptation is slow from low doses to high doses. This is because some people (especially first-time users) may feel more sleepy

If you start with a lower dose, you will need to monitor your growth rate, slowly reach a steady state, and then increase the dose to reach an equilibrium state until you reach your goal.

Length of service cycle: more than 3 months

Bodybuilders can take compounds all year round, but compounds aren't cheap after all. To save money, Bodybuilders can use it at intervals, and it will also give very good results.Stop using for 3 months and stop using in case of serious side effects.

Dosage and Cycles for Women

Dosage:

Beginner: 5 mg per day

Intermediate: 12.5 mg per day

Advanced: 25 mg per day

MK677 powder for bodybuilding has a half-life of 6 hours, so it is best to use it in different doses. However, if side effects such as increased hunger and drowsiness become excessive, bodybulders should reduce the total daily dose around 6pm each day.

Because of the compound's sleep-enhancing properties, the adaptation is slow from low doses to high doses. This is because some people (especially first-time users) may feel more sleepy

If you start with a lower dose, you will need to monitor your growth rate, slowly reach a steady state, and then increase the dose to reach an equilibrium state until you reach your goal.

Length of service cycle: more than 3 months

Bodybuilders can take compounds all year round, but compounds aren't cheap after all. To save money, Bodybuilders can use it at intervals, and it will also give very good results.Stop using for 3 months and stop using in case of serious side effects.

MK677 SARM Bulking & Cutting Stacks

Bodybuilders often meet specific needs when using bodybuilding supplements. MK677 is a significantly expanded SARM, often stacked with other SARMs, such as RAD 140 or Ligandrol, for faster expansion.

MK-677 increases growth hormone, so it's the best muscle building stack, but it maintains lean muscle mass while cutting. Having said that, in our personal opinion, this is the best for users trying to get quality, as the MK 677 is one of the best SARMs out there.

MK677 SARM FAQ

What color is the MK677 powder?

Most of the MK677 powder is white, but some manufacturers produce yellow, which is normal. Because each company's production process will be different.

Does MK677 have androgenic effects?

While most supplement manufacturers sell it as a SARM, it's not actually a SARM, it's a growth hormone secretagogue (GHS) receptor agonist that works by promoting growth hormone (GH) and islet-like growth factor 1 (IGF secretion-1) will work and will not affect the body's androgens.

How to take MK677?

MK677 powder for bodybuilding is an oral non-peptide growth hormone secretagogue (GHS) receptor agonist, it does not require injection like peptide growth hormone secretagogue (GHS) receptor agonists, so it can reduce the trouble of many injections. Due to MK 677 has a half-life of 6 hours, and bodybuilders need to take two daily doses.

Does MK677 require PCT?

No need for PCT. Bodybuilders needs to do post-cycle PCT after a cycle of steroids or SARMs, as both drugs will maintain the bodybuilder's ability to produce testosterone at all times. However, MK677 improves bodybuilding by promoting the release of growth hormone, so bodybuilders do not need to do PCT.

How long will the MK 677 last?

The efficacy of MK-677 increases and improves with long-term use. The recommended cycle length is 3-6 months for best results. Some people like to use MK-677 all year round, but it is all personal and needs to pay attention to their own situation. If they feel uncomfortable with strong side effects, they should stop immediately.

How to tell if it is MK677 powder manufacturer?

There are many supplement vendors selling MK677 in the market, and they all call themselves manufacturers. MK 677 is often difficult for bodybuilders to distinguish the real from the fake. So how can you get a high-quality MK 677 at a competitive price?

Distinguish bodybuilders from the following aspects：

1. Manufacturers need to provide product photos. Most of the MK677 powder is pure white powder. Some manufacturers make the MK677 powder light yellow due to the difference in the production process.
2. The manufacturer needs to provide a test report, including HPLC, HNMR and other product information.
3. Order from the sample, and judge according to the manufacturer's delivery time and delivery speed.
4. Real manufacturers tend to have very competitive prices.

Where to buy MK677 SARMs powder？

1. Please send me your purchase request via the message board below the website. In order to give you a more accurate quotation, I need to know the following information: product name, order quantity, delivery country, quality requirements, etc.
2. When we agree on the product details, product price and shipping details, we will ship the goods to the freight forwarder within 24 hours after receiving your payment. Usually 2-3 days, the goods will arrive at the freight forwarder, then we will provide you the waybill number of the goods.
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