GW501516, also known as Cardarine, is a PPARδ receptor agonist discovered in the 1990s. It was originally developed to treat obesity, diabetes and cardiovascular disease. But as research continues to deepen, GW501516(Cardarine) has gradually become one of the most popular fats reducing SARMs. It is a selective agonist of the PPARδ receptor with high affinity for PPARδ. In rats treated with GW501516, increased fatty acid metabolism in skeletal muscle and protection against diet-induced obesity and type II diabetes were observed. In rhesus monkey experiments, GW501516 increased high-density lipoprotein (HDL) and decreased low-density lipoprotein (LDL).
Bodybuilders significantly improved blood cholesterol levels after using GW501516 (Cardarine), a drug that stimulates the expression of genes involved in glucose and fatty acid metabolism. GW501516 activates PPARδ receptors, increases lipoprotein lipase and apolipoproteins in the liver, thereby reducing low-density lipoprotein (LDL), reducing the level of triglycerides in the blood, releasing fatty acids that oxidize fat cells, that is Everyone is talking about burning fat. In addition, when the PPARδ receptor is activated, high-density lipoprotein (HDL) in the liver increases, and the increase in high-density lipoprotein (HDL) can transport blood lipids in the blood to the liver for metabolism. Overall, GW501516, as a PPARδ receptor agonist, can increase high-density lipoprotein (HDL) and reduce low-density lipoprotein (LDL) to increase the rate of fat loss and improve cholesterol status in the body.
The usual dose of GW501516 is 20 mg per day for 2-3 months, and due to its half-life of 20-24 hours, Bodybuilders can take it once a day. GW501516 can also be added to a fat loss medication cycle to increase fat loss. In addition, GW501516 can also be added to the circulation of Trenbolone, because many people will experience symptoms such as coughing and breathing difficulties with Trenbolone. Using GW501516 can improve the cardiovascular endurance of bodybuilders, so that you have more endurance to participate in sports. In addition, as we all know, carbohydrates will make bodybuilders maintain a higher energy level every day, but in the process of losing fat, bodybuilders need to maintain a low-carbon state. Under the low-carbon state, energy will inevitably be lost, which will lead to weakened endurance, so use GW501516 Losing fat will improve your stamina and improve your aerobic performance, as well as help keep your energy levels and stamina high. For women, when their weight is less than 55KG, 10mg a day can achieve a good state.
GW501516 (Cardarine) is not a hormone, so it does not suppress its own production of testosterone, so it does not give Bodybuilders the side effects of using anabolic steroids. Bodybuilders are also not required to do PCT after the cycle is over. Although GW501516 (Cardarine) has basically no side effects, there are still some potential risks in the long-term use of bodybuilders.