The steroid-selective androgen receptor modulator (SARM) synthesized by SARM YK11, a genetically selective partial agonist of the androgen receptor (AR), was discovered in 2011 and soon gained the most Praise for one of the powerful compounds. To better explain this, we need to understand Myostatin in detail.
Myostatin, also known as growth differentiation factor 8 (GDF8), is a protein encoded by the MSTN gene in humans and belongs to the myokine family, which is produced and released by muscle cells and acts on muscle cells to inhibit muscle growth. Basically, all humans have Myostatin in their body, it inhibits the growth of our muscles, very few people and animals are born without this hormone, Myostatin keeps smashing muscle tissue in the human body, so it organizes our muscle growth.
Since Myostatin was discovered, scientists have been trying to suppress its effects. Theoretically, if there was a compound that inhibited the effects of Myostatin on the body, then we could get a lot of muscle growth in the body, even more than the muscle gains from hard work and steroid use. So is there such a substance that can inhibit Myostatin? The answer is yes, that is YK11.
YK11 is a synthetic steroid-selective androgen receptor modulator (SARM), the world's first true Myostatin inhibitor. People taking SARM YK11 all had the same result: massive muscle growth in a very short period of time. This made it popular with Bodybuilders.
During the use of Bodybuilders, in order to obtain better results, it is often necessary to have a detailed understanding of the dosage of SARM YK11. Due to the short half-life of YK11, it is recommended that Bodybuilders take YK11 several times a day when taking YK11. The following are the recommended doses:
From Week 1 to Week 4: 5mg in the morning and 5mg in the evening
From week 5 to week 8: Daily dose increased to 15mg. 5mg in the morning, 5mg before Bodybuilding, 5mg in the evening.
From week 9 to Week 12 (this cycle is only available for professional Bodybuilders. Generally, YK11 cycle of 8 weeks is enough for Bodybuilders): Increase the daily dose to 20mg. 10mg in the morning, 5mg before Bodybuilding, 5mg in the evening.
Although SARM YK11 has a powerful muscle-building ability, it also has side effects. During use, YK11 shows a slight increase in liver values, so users need to drink more water or use a good liver supplement such as milk thistle. In addition, YK11 is a steroid-selective androgen receptor modulator and is part of the chemical structure DHT, the more potent form of testosterone. Therefore, YK11 mimics androgen and has a certain inhibitory effect on endogenous testosterone. However, YK11 mainly targets muscle tissue, mainly inhibits Myostatin, and has few androgenic side effects. But bodybuilders can ignore androgenic side effects of YK11 compared to anabolic steroids