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GW0742 SARM is similar to GW501516 (Cardarine), they are all agonists of PPARδ receptors, PPARs belong to a subfamily of transcriptional nuclear factors, so far, three PPAR isoforms have been identified: α, β/δ and γ , encoded by different genes and distributed in various tissues. They play an important role in metabolic processes, converting our fat into a source of energy and increasing the oxidative capacity of our muscles. Let's take a closer look at GW0742 SARM Benefits, GW0742 SARM Dosage and GW0742 SARM Side Effects.
|Product Name: GW0742|
|BP: 591.5±60.0 °C(Predicted)|
|Density: 1.46±0.1 g/cm3(Predicted)|
GW0742 is a highly selective and potent agonist of PPARδ, a nuclear receptor protein that plays a crucial role in regulating human metabolism, cell development and cell differentiation. It belongs to the same PPARδ agonist as GW501516 (Cardarine), the structural formulas of these two compounds are not much different, and there is only a small difference between them by one atom. The following figure is the molecular structure comparison of GW0742 and GW501516 (Cardarine).
As can be seen from the molecular structure diagram, their structures are basically the same. Therefore, the two compounds may provide the same benefits, and their side effects may be similar. Hence the reason why GW0742 is also known as the successor to GW501516 (Cardarine).
GW0742 is a PPARδ receptor agonist that works like most PPARδ receptors. PPARδ receptors perform two key functions at Bodybuilders: convert fat in our system into energy and put our muscles into an oxidative state to increase their endurance to training. And GW0742 is a PPARδ receptor agonist, which means that GW0742, at least in theory, should increase our endurance. Although, we haven't seen any definitive studies showing this, but Bodybuilders has experienced the effects of GW0742 on endurance and muscle response to strength training during daily training.
Research shows that GW0742 can improve the body's insulin sensitivity. A study in rats showed that the bodies of mice given GW0742 were more sensitive to insulin than those given a placebo.
GW0742 SARM Benefits
Since the development of GW0742 SARM, people have continued to explore it. Studies have found that GW0742 can reduce total cholesterol in the body, improve blood lipid levels, and reduce intestinal inflammation. Most importantly, GW0742 has been shown to alleviate cardiac hypertrophy.
The gut is an important part of the human body, and an inflamed gut can cause many problems for patients in daily life, including low blood sugar, irregular fatigue, unexplained nausea, chronic constipation and acne. If you are experiencing some of these health conditions, the GW0742 will help you.
A study showed that GW0742 successfully helped suppress cardiac hypertrophy, and in addition to stopping the disease, GW0742 reversed the damage it caused. Cardiac hypertrophy is known to be one of the most dangerous forms of heart disease and results from an increase in the size of the cells that form the heart muscle. It causes abnormal enlargement of the heart muscle, which can lead to heart failure and even sudden death if left untreated. This can therefore be improved by ingesting GW0742.
There are "good" and "bad" cholesterol in the human body, and their respective amounts can be seen through the ester map. "Good" cholesterol reduces the body's risk of cardiovascular disease, and "bad" cholesterol, such as triglycerides, increases the risk of heart attack, heart attack and stroke. Studies have shown that at low doses, GW0742 can enhance lipid metabolism in the heart, which means it can better handle triglycerides, resulting in improved lipid profiles.
Diabetes is a metabolic disease in humans. Hundreds of millions of people around the world are in a state of pre-diabetes. With its development, it will lead to a more deadly disease-diabetes. Fortunately, a study in rats showed that GW0742 was found to reverse the decline in glucose levels in the body, which has the potential to become a future replacement for insulin in the fight against diabetes.
With the development of society and the improvement of people's living standards, there are more and more obese people, and the incidence of hypertension is also increasing. Millions of people die of hypertension every year, so it deserves our attention.
In one study, GW0742 show to prevent hypertension caused by diet-induced obesity. This is good news for mankind.
GW0742 SARM, and researchers have also been studying its dosage. In the study, the intake of rats was between 5-30 mg/kg, but this does not give us more information on the dosage used. Since GW0742 is similar in molecular structure to GW501516 (Cardarine), we recommend following the same protocol as GW501516 (Cardarine) if you plan to use it.
Taken for no more than 8 weeks, the dose is 10mg per day.
Regarding the half-life of GW0742, although there is no detailed data, since its molecular structure is basically the same as that of GW501516 (Cardarine), its half-life should be 24 hours.
Any drug has side effects. When using drugs, we often see precautions and adverse reactions in the instructions. GW0742 is no exception, the compound activates calcineurin in the body, thereby increasing the size of the heart, which can be very dangerous, and this side effect doesn't take weeks to materialize, with mice experiencing calcineurin after just 24 hours of ingestion. develop a larger heart. But the symptoms gradually disappeared after a few weeks of stopping the medication.
In addition to this, GW0742 has no other side effects reported for the time being.
Through the above introduction, we learned that GW0742 is a highly selective PPARδ receptor agonist, which has a similar molecular structure to GW501516 (Cardarine), so they have similar advantages and side effects.
Studies have shown that GW0742 can strengthen the heart, improve blood lipid levels, prevent high blood pressure, and may be used as an anti-diabetic drug in place of insulin in the future.
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