LGD 4033 side effects：What you need to know before using it?

Pursuing advantages and avoiding disadvantages is the fundamental principle for the survival and development of organisms. When people use a drug, they often pay attention to its benefits, but its side effects cannot be ignored. LGD 4033 is an oral non-steroidal selective androgen receptor modulator, a compound that targets specific androgen receptors in the body, the main function is to increase muscle growth and bone density, and for Bodybuilders, it has a powerful Therefore, LGD 4033 is becoming more and more popular with Bodybuilders. Although it is powerful, the LGD 4033 side Effects cannot be ignored.

LGD 4033 side effects

Two known minor side effects associated with LGD 4033 are headache and dry mouth. However, more troublesome side effects can also occur.

1.Cholesterol

LGD 4033 may lead to lower HDL cholesterol. The researchers observed users who used a dose of 1 mg/day and found that the HDL cholesterol in the user's body was reduced by nearly 40% in just 3 weeks, and the reduction in HDL cholesterol may be Increases the risk of arteriosclerosis and harms heart health. This change may be attributed to the need for oral administration of LGD 4033 to pass through the liver by stimulating the enzyme hepatic lipase, thereby causing this change in HDL cholesterol. In this study, researchers found that LDL cholesterol levels remained stable, while serum triglycerides were reduced by 15%, possibly reducing some cardiovascular stress.

2.Testosterone Suppression

Although LGD 4033 is a non-steroidal drug, it still inhibits natural testosterone levels by selectively binding to androgen receptors. In trials where 1 mg/day of LGD 4033 was given, participants' total testosterone levels dropped by 50%. Free testosterone also experienced a similar 40% drop.

The user's endogenous testosterone does not return to normal levels until a period of time after the drug is discontinued.

Therefore, users need to perform PCT with appropriate drugs after using LGD 4033 cycles.

3.Hepatotoxicity

In a phase 1 clinical trial of 76 adult men, through the observation of different doses, the change in the user's net weight gain was positively correlated with the dose, and obvious side effects occurred in the afternoon of the 21-day test, which can be seen the hepatotoxicity of LGD 4033 was minimal.

Through the above introduction, we can understand the side effects of SARM LGD 4033, but due to the difference in human body constitution, different people have different tolerance to LGD 4033. Users can use it according to their own conditions. Once serious side effects are found, please stop the drug immediately. , and consult a doctor.